Genetic and Epigenetic Studies in Diabetic Kidney Disease

Kidney disease is a worldwide health crisis, while diabetes kidney disease (DKD) has become a leading cause of end stage renal disease (ESRD). DKD is a microvascular complication and occurs in 30-40% of diabetes patients. Epidemiological investigation and clinical observation on the familial clustering and heritability in DKD have implicated that genetic susceptibilities are involved in the pathogenesis. Furthermore, DKD is a progressive and...