Anti-inflammatory effects of blueberry extract in microglial cells

Background: Microglia (MG), the immunocompetent cells of the CNS, respond to brain injury activating and modifying their morphology. Microglia can exist broadly between two different activation states, namely the classical (M1) and the alternative activated (M2) phenotype. The first one is characterized by the production of pro-inflammatory cytokines, in contrast, the latter is characterized by the production of anti-inflammatory cytokines...