Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia

Case series suggest favorable results of peroral endoscopic myotomy (POEM) for treatment of patients with achalasia. Data comparing POEM with pneumatic dilation, the standard treatment for patients with achalasia, are lacking.To compare the effects of POEM vs pneumatic dilation as initial treatment of treatment-naive patients with achalasia.This randomized multicenter clinical trial was conducted at 6 hospitals in the Netherlands, Germany,...