D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy

Volume: 11, Issue: 14, Pages: 4943 - 4969
Published: Jul 15, 2019
Abstract
Although many mechanisms have been proposed for diabetic encephalopathy in type 2 diabetes mellitus (T2DM), the risk factors for cognitive impairment in type 1 diabetes mellitus (T1DM) are less clear. Here, we show that streptozotocin (STZ)-induced T1DM rats showed cognitive impairment in both Y maze and Morris water maze assays, accompanied with D-ribose was significantly increased in blood and urine, in addition to D-glucose. Furthermore,...
Paper Details
Title
D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy
Published Date
Jul 15, 2019
Journal
Volume
11
Issue
14
Pages
4943 - 4969
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