B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease
Volume: 145, Issue: 3, Pages: 968 - 981.e14
Published: Mar 1, 2020
Abstract
BackgroundIgG4-related disease (IgG4-RD) is a fibroinflammatory condition marked by rapid clinical improvement after selective depletion of B lymphocytes with rituximab. This feature suggests that B cells might participate in fibrogenesis and wound healing.ObjectiveIn the present work we aimed to demonstrate that B lymphocytes contribute directly to tissue fibrosis in patients with IgG4-RD.MethodsTotal circulating CD19+ B lymphocytes, naive B...
Paper Details
Title
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease
Published Date
Mar 1, 2020
Volume
145
Issue
3
Pages
968 - 981.e14
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