Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Abstract
Tumor metastasis is a major contributor to the death of cancer patients. It is driven not only by the intrinsic alterations in tumor cells, but also by the implicated cross-talk between cancer cells and their altered microenvironment components. Tumor-associated macrophages (TAMs) are the key cells that create an immunosuppressive tumor microenvironment (TME) by producing cytokines, chemokines, growth factors, and triggering the inhibitory...
Paper Details
Title
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Published Date
Jul 12, 2019
Volume
12
Issue
1
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