Synthesis and characterization of dual pH-and thermo-responsive graphene-based nanocarrier for effective anticancer drug delivery

In the present work, the surface of graphene oxides (GO) have been modified with biodegradable and hydrophilic polymeric compounds, poly(N-vinylcaprolactam) (PNVCL) and poly(glycolic acid) over covalent functionalization for effectual loading and release of oxaliplatin anticancer drug. The oxaliplatin was loaded onto the graphene oxide surface of GO-PNVCL-PGA composite by the π-π interactions. The release profile of oxaliplatin from GO-PNVCL-PGA...