PACAP27 induces migraine-like attacks in migraine patients
Abstract
Introduction Pituitary adenylate cyclase-activating polypeptide (PACAP) is found in two functional isoforms, namely PACAP38 and PACAP27. The migraine-inducing properties of PACAP38 are well studied. However, it is not known whether the lesser-known and under-studied protein isoform, PACAP27, can also induce migraine attacks. Here, we studied the effect of human PACAP27 infusion on induction of migraine in a provocation model. Methods In a...
Paper Details
Title
PACAP27 induces migraine-like attacks in migraine patients
Published Date
Jul 12, 2019
Journal
Volume
40
Issue
1
Pages
57 - 67
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