Single-cell reconstruction of follicular remodeling in the human adult ovary
Abstract
The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus. The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian tissue homeostasis, remain elusive. We have performed single-cell RNA-sequencing using human adult ovaries to provide a map of the molecular signature of growing and regressing follicular populations. We have identified different types of granulosa and theca cells and...
Paper Details
Title
Single-cell reconstruction of follicular remodeling in the human adult ovary
Published Date
Jul 18, 2019
Journal
Volume
10
Issue
1
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