Inheritance and variability of kinetic gene expression parameters in microbial cells: modeling and inference from lineage tree data
Abstract
Motivation Modern experimental technologies enable monitoring of gene expression dynamics in individual cells and quantification of its variability in isogenic microbial populations. Among the sources of this variability is the randomness that affects inheritance of gene expression factors at cell division. Known parental relationships among individually observed cells provide invaluable information for the characterization of this extrinsic...
Paper Details
Title
Inheritance and variability of kinetic gene expression parameters in microbial cells: modeling and inference from lineage tree data
Published Date
Jul 1, 2019
Journal
Volume
35
Issue
14
Pages
i586 - i595
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Notes
History