Solid Pseudopapillary Neoplasms of the Pancreas: Clinicopathologic and Radiologic Features According to Size.

Published on Jul 16, 2019in American Journal of Roentgenology3.013
· DOI :10.2214/AJR.18.20715
Riccardo De Robertis17
Estimated H-index: 17
,
Giovanni Marchegiani29
Estimated H-index: 29
(University of Verona)
+ 4 AuthorsMirko D'Onofrio58
Estimated H-index: 58
(University of Verona)
Sources
Abstract
OBJECTIVE. The purpose of this study was to retrospectively analyze and correlate clinicopathologic and radiologic features of resected solid pseudopapillary neoplasms of the pancreas according to ...
📖 Papers frequently viewed together
18 Citations
4 Authors (Shudong Hu, ..., Kemin Chen)
7 Citations
References6
Newest
#1Hao Gao (Nanjing Medical University)H-Index: 4
#2Yong Gao (Nanjing Medical University)H-Index: 4
Last. Yi Miao (Nanjing Medical University)H-Index: 33
view all 7 authors...
Background: Pancreatic solid pseudopapillary tumors (SPTs) are rare neoplasms with low-grade malignancy. The main treatment for them is surgical resection. However, some SPTs relapse after resection. The risk factors associated with the recurrences of resected SPTs remain controversial to date. We performed a systematic review and meta-analysis to identify the risk factors of the recurrences of pancreatic SPTs. Materials and Methods: We searched PubMed, EMBASE, and the Cochrane Library from thei...
15 CitationsSource
#1Zeljka JutricH-Index: 8
#2Yelena Rozenfeld (Providence Health & Services)H-Index: 9
Last. Ronald F. WolfH-Index: 22
view all 8 authors...
Introduction Current literature addressing the treatment of solid pseudopapillary neoplasms (SPNs) of the pancreas is limited, particularly for patients with distant metastases. We aimed to define predictive indicators of survival in a large series of patients and assess the outcome of patients with distant metastases.
22 CitationsSource
#1Gopinathan Anil (NUS: National University of Singapore)H-Index: 12
#2Junwei ZhangH-Index: 1
Last. Min En NgaH-Index: 1
view all 4 authors...
PURPOSE: We aimed to evaluate the imaging features of solid pseudopapillary neoplasm (SPN) of the pancreas with an emphasis on radiologic-pathologic correlation. METHODS: Ten patients (all female; mean age, 32 years) with histologic or cytologic diagnosis of SPN encountered between January 2007 and December 2013 were included in this study. Preoperative computed tomography (CT) images were reviewed for location, attenuation, enhancement pattern, margin, shape, size, morphology, presence of capsu...
18 CitationsSource
#1Giovanni Marchegiani (University of Verona)H-Index: 29
#2Stefano Andrianello (University of Verona)H-Index: 16
Last. Roberto Salvia (University of Verona)H-Index: 52
view all 15 authors...
Abstract Since their introduction in the WHO classification, the incidence of solid pseudopapillary tumors (SPTs) of the pancreas has progressively increased, mainly because of the widespread use of cross-sectional imaging. Few recent studies have analyzed the biological behavior of SPTs, but reliable data on long-term follow-up are needed. Retrospective analysis of two Institutions with high caseload, The Department of General Surgery-Pancreas Institute, University of Verona Hospital Trust and ...
38 CitationsSource
#1Jee Hyun Baek (SNU: Seoul National University)H-Index: 18
#2Jeong Min LeeH-Index: 83
Last. Byung Ihn ChoiH-Index: 89
view all 8 authors...
The imaging features of small solid pseudopapillary tumors (SPTs) were different from those of typical SPTs, and the small SPTs usually appeared as purely solid lesions with sharp margins and gradual enhancement, without secondary changes to the neighboring pancreatic parenchyma.
76 CitationsSource
#1Robert C.G. Martin (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 81
#2David S. Klimstra (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 145
Last. Kevin C. Conlon (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 78
view all 4 authors...
Background: Solid-pseudopapillary tumors (SPTs) of the pancreas have been reported as rare lesions with “low malignant potential” occurring mainly in young women. This study was designed to define the clinicopathological characteristics and the effect of surgical intervention.
336 CitationsSource
Cited By7
Newest
#1Ji Su Kim (Yonsei University)H-Index: 3
#2Emmanuel Ii Uy Hao (UP: University of the Philippines Diliman)H-Index: 1
Last. Chang Moo Kang (Yonsei University)H-Index: 30
view all 7 authors...
Predicting the aggressiveness of solid pseudopapillary neoplasms (SPNs) remains an important goal. The present study aimed to identify perioperative factors that can predict patients who will develop clinically aggressive SPN. Records of individuals with pathologically confirmed SPN from 2006 to 2017 were obtained from the patient registry database of Yonsei University, Severance Hospital. For this study, aggressive behavior was defined as SPN that had recurred, metastasized, or involved adjacen...
Source
#1Hongchun Chen (Bengbu Medical College)
#2Yuchen Huang (Bengbu Medical College)
Last. Zhenzhong Feng (Bengbu Medical College)H-Index: 2
view all 9 authors...
Purpose Solid-pseudopapillary neoplasm (SPN) of the pancreas, a rare tumor, has low malignant potential. However, some patients develop metastasis and recurrence after resection, with aggressive biological behaviors. This study aimed to explore the features and risk factors associated with the aggressive biological behaviors of SPNs. Patients and Methods We retrospectively analyzed the clinicopathological and long-term follow-up data of 63 patients diagnosed with SPN at the First Affiliated Hosp...
1 CitationsSource
#1Kheng Song LeowH-Index: 2
Last. Cher Heng Tan (NTU: Nanyang Technological University)H-Index: 9
view all 7 authors...
Source
#1Tao Song ('SMMU': Second Military Medical University)H-Index: 1
#2Qian-Wen Zhang ('SMMU': Second Military Medical University)
Last. Jianping Lu ('SMMU': Second Military Medical University)H-Index: 16
view all 10 authors...
BACKGROUND This study aims to investigate the value of radiomics parameters derived from contrast enhanced (CE) MRI in differentiation of hypovascular non-functional pancreatic neuroendocrine tumors (hypo-NF-pNETs) and solid pseudopapillary neoplasms of the pancreas (SPNs). METHODS Fifty-seven SPN patients and twenty-two hypo-NF-pNET patients were enrolled. Radiomics features were extracted from T1WI, arterial, portal and delayed phase of MR images. The enrolled patients were divided into traini...
3 CitationsSource
#1José Celso Ardengh (USP: University of São Paulo)H-Index: 17
#2César Vivian Lopes (Santa Casa Hospital)H-Index: 15
Last. Marcel Autran C. MachadoH-Index: 25
view all 4 authors...
Background and aims Preoperative diagnostic imaging of pancreatic solid pseudopapillary neoplasms (SPN) is challenging. A few studies have investigated the role of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis of SPN. We investigated the diagnostic yield of cell blocks and immunohistochemistry (IHC) for SPN using EUS-FNA specimens without cytological evaluation. Patients and methods We retrospectively analyzed the histopathology records of patients with suspecte...
3 CitationsSource
#1Nasir Ud Din (Aga Khan University Hospital)H-Index: 12
#2Shabina Rahim (Aga Khan University Hospital)H-Index: 1
Last. Zubair Ahmad (Aga Khan University Hospital)H-Index: 14
view all 5 authors...
Pancreatic Solid Pseudopapillary Neoplasms (SPNs) are rare low-grade malignant tumors with a marked preponderance for young females. Objective was to describe the morphology, differential diagnosis, and prognosis of SPNs in patients under 20 years of age and present a detailed review of literature. A total of 29 cases in patients under 20 years of age reported as SPN during the period January 2014 to December 2019, were included in the study. These included 19 resection specimens, 4 incision bio...
Source
#1Amin Dalili (MUMS: Mashhad University of Medical Sciences)H-Index: 1
#2Mohsen Aliakbarian (MUMS: Mashhad University of Medical Sciences)H-Index: 9
Last. Sara Raji (MUMS: Mashhad University of Medical Sciences)H-Index: 1
view all 5 authors...
Introduction. Solid pseudopapillary neoplasm (SPN) is a rare and indolent pancreatic tumor with low malignant potential which frequently occurs in reproductive-age females. Complete resection is almost always the curative option. Case Presentation. We present a 20-year-old woman with acute epigastric pain and vomiting in multiple episodes. Abdominal ultrasound showed a hypoechoic lesion with the probable source in the pancreas. Following that, CT scans and Endoscopic Ultrasound (EUS) manifested ...
Source