Does Pioglitazone Lead to Neutrophil Extracellular Traps Formation in Chronic Granulomatous Disease Patients?
Abstract
Nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase, enzyme complex responsible for Reactive oxygen species (ROS) production is defective in chronic granulomatous disease (CGD) patients. This enzyme helps in antimicrobial host defence by phagocytes. CGD patients have inability to form Neutrophil extracellular traps (NETs), which are composed of granule derived proteins from neutrophils decorated with decondensed chromatin. Mitochondria...
Paper Details
Title
Does Pioglitazone Lead to Neutrophil Extracellular Traps Formation in Chronic Granulomatous Disease Patients?
Published Date
Jul 31, 2019
Journal
Volume
10
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