Original paper

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Volume: 38, Issue: 1
Published: Jul 18, 2019
Abstract
Molecular markers for prostate cancer (PCa) are required to improve the early definition of patient outcomes. Atypically large extracellular vesicles (EVs), referred as "Large Oncosomes" (LO), have been identified in highly migratory and invasive PCa cells. We recently developed and characterized the DU145R80 subline, selected from parental DU145 cells as resistant to inhibitors of mevalonate pathway. DU145R80 showed different proteomic profile...
Paper Details
Title
Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation
Published Date
Jul 18, 2019
Volume
38
Issue
1
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