PPAR-<bold><roman>γ</roman></bold> activation increases insulin secretion independent of CASK in INS-1 cells

Volume: 51, Issue: 7, Pages: 715 - 722
Published: Jun 1, 2019
Abstract
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is expressed in pancreatic β cells and is involved in insulin secretion. However, the precise mechanisms remain unclear. Calcium/calmodulin-dependent serine protein kinase (CASK), which plays a vital role in the anchoring of insulin granules on pancreatic β cell membrane, is probably a downstream of the transcription factor PPAR-γ. The aim of the present study was to investigate the...
Paper Details
Title
PPAR-<bold><roman>γ</roman></bold> activation increases insulin secretion independent of CASK in INS-1 cells
Published Date
Jun 1, 2019
Volume
51
Issue
7
Pages
715 - 722
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