Silicon photomultiplier

Photomultiplier

Physics

Pathology

Image resolution

Optics

Full width at half maximum

Resolution (logic)

Scintillator

Artificial intelligence

Focus (optics)

Alternative medicine

Coincidence

Lyso-

Computer science

Medicine

Detector

Physics in Medicine and Biology

The performance of a light sharing and recirculation mechanism that allows the extraction of depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In parallel, a method to optimize the coincidence time resolution (CTR) of PET detectors by use of the DOI information is proposed and tested. For these purposes, a dedicated 64-channels readout setup has been developed with intrinsic timing resolution of 16 ps FWHM. Several PET modules have been produced, based on LYSO:Ce scintillators and commercial silicon photomultiplier (SiPM) arrays, with [Formula: see text] mm2 individual SiPM size. The results show the possibility to achieve a timing resolution of 157 ps FWHM, combined with the already demonstrated spatial resolution of 1.5 mm FWHM, DOI resolution of 3 mm FWHM, and energy resolution of 9% FWHM at 511 keV, with 15 mm long crystals of section [Formula: see text] mm2 and [Formula: see text] mm2. At the same time, the extraction of the DOI coordinate has been demonstrated not to deteriorate the timing performance of the PET module.

On light sharing TOF-PET modules with depth of interaction and 157 ps FWHM coincidence time resolution