Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo
Abstract
Since it was introduced 20 years ago, tamoxifen-inducible genetic recombination in vivo has become a standard tool in many fields. This technique has great utility, allowing precise temporal and spatial gene recombination mediated by expression of a Cre recombinase-oestrogen receptor hormone binding domain fusion protein. It is frequently used in developmental biology, either for accurate spatio-temporal gene deletion or for lineage-labelling....
Paper Details
Title
Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo
Published Date
Jun 27, 2019
Journal
Volume
53
Issue
6
Pages
630 - 633
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Notes
History