SUN-230 ASSOCIATION BETWEEN ESTIMATED PROTEIN INTAKE AND SINGLE-NEPHRON GLOMERULAR FILTRATION RATE IN HEALTHY ADULTS

High protein intake can increase renal plasma flow and glomerular filtration rate (GFR) in response to excretory overload, which may exacerbate kidney disease progression. Glomerular hypertrophy has been shown to be closely associated with sclerosis at the level of a single nephron in experimental models. However, the mechanisms by which an excessive protein diet causes glomerular hyperfiltration and increases single-nephron GFR (SNGFR) have not...