Clinical effectiveness of switching between DPP-4 inhibitors in patients with type 2 diabetes mellitus

Dipeptidyl peptidase-4 inhibitors (DPP-4Is) can be classified into three categories according to their binding subsites. We wished to clarify the efficacy of switching between DPP-4Is according to their binding subsites.We undertook a retrospective study of the medical records of patients who switched from one DPP-4I to another.Among 62 patients eligible for study inclusion, the mean change in the glycated hemoglobin (HbA1c) level between...