Iron-regulatory genes are associated with Neuroimaging measures in HIV infection
Abstract
The pathogenesis of HIV-associated neurocognitive impairment (NCI) may involve iron dysregulation. In 243 HIV-seropositive adults without severe comorbidities, we therefore genotyped 250 variants in 20 iron-related genes and evaluated their associations with magnetic resonance imaging measures of brain structure and metabolites, including measures previously linked to NCI. Multivariable regression analyses examined associations between genetic...
Paper Details
Title
Iron-regulatory genes are associated with Neuroimaging measures in HIV infection
Published Date
Jul 3, 2019
Journal
Volume
14
Issue
5
Pages
2037 - 2049
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