Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles
Abstract
Mesenchymal stem or stromal cells (MSC) have proven immunomodulatory properties toward B cell activation and induce regulatory B cells (Breg), through a dual mechanism of action that relies both on cell contact and secreted factors. One of them are MSC-derived extracellular vesicles (EVs), membrane nanovesicles that mediate cell communication and typically reflect the phenotype of the cell of origin. MSC-EVs could resemble MSC functions, and are...
Paper Details
Title
Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles
Published Date
Jun 6, 2019
Journal
Volume
10
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