Influence of the graft density of hydrophobic groups on thermo-responsive nanoparticles for anti-cancer drugs delivery B Biointerfaces
Abstract
A series of deoxycholate-chitosan-hydroxybutyl (DAHBCs) with different degrees of substitution (DS) of hydrophobic deoxycholate (DOCA) were successfully synthesized. The lower critical solution temperature (LCST) of various DAHBCs could be adjusted from 35.4°C to 42.1°C by controlling the graft density of DOCA. DAHBCs could self-assemble into nanoparticles (NPs) which gradually evolved from irregular aggregates to spherical particles with the...
Paper Details
Title
Influence of the graft density of hydrophobic groups on thermo-responsive nanoparticles for anti-cancer drugs delivery B Biointerfaces
Published Date
Jan 1, 2016
Journal
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