The metalloproteinase ADAM15 is upregulated by shear stress and promotes survival of endothelial cells

Volume: 134, Pages: 51 - 61
Published: Sep 1, 2019
Abstract
Reduced shear stress resulting from disturbed blood flow can impair endothelial integrity and drive the development of vascular inflammatory lesions. Metalloproteinases of the ADAM family have been implicated in the regulation of cell survival and inflammatory responses. Here we investigate the mechanism and function of ADAM15 upregulation in primary flow cultured endothelial cells. Transcriptomic analysis indicated that within the ADAM family...
Paper Details
Title
The metalloproteinase ADAM15 is upregulated by shear stress and promotes survival of endothelial cells
Published Date
Sep 1, 2019
Volume
134
Pages
51 - 61
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.