Oximes as pretreatment before acute exposure to paraoxon
Abstract
Organophosphates, useful agents as pesticides, also represent a serious danger due to their high acute toxicity. There is indication that oximes, when administered before organophosphate exposure, can protect from these toxic effects. We have tested at equitoxic dosage (25% of LD01 ) the prophylactic efficacy of five experimental (K-48, K-53, K-74, K-75, K-203) and two established oximes (pralidoxime and obidoxime) to protect from mortality...
Paper Details
Title
Oximes as pretreatment before acute exposure to paraoxon
Published Date
Jul 2, 2019
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