Preface: A New Disease?

Published on Jan 1, 2019
· DOI :10.1007/978-3-030-11815-0_1
At the Scientific Sessions of the American Diabetes Association in 1992, Professor Gian Franco Bottazzo delivered the Banting Lecture, in which he announced that diabetes was “a new disease,” based on criteria originally described by Mirko D. Grmek in his classical book about the history of AIDS:
#1Amnon Zung (HUJI: Hebrew University of Jerusalem)H-Index: 16
#2Wasef Na’amnih (CDC: Centers for Disease Control and Prevention)H-Index: 6
Last. Orit Blumenfeld (CDC: Centers for Disease Control and Prevention)H-Index: 7
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BACKGROUND: The global rise in incidence of type 1 diabetes (T1D) is too rapid to be attributed to susceptible genetic background, pinpointing a significant role for environmental factors. Unlike the theory that the need for genetic susceptibility has lessened over time, we hypothesized that the rise in T1D incidence is faster in a genetically susceptible population. SUBJECTS AND METHODS: The study population comprised of 5080 patients aged 0 to 17 years who were reported to the National Israel ...
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Epigenetics in Disease Prevention and Mitigation Epigenetics is the regulation of gene expression through alterations in DNA or associated factors (other than the DNA sequence). These factors control the diverse manifestations of diseases. Insights into epigenetic modification may lead to new therapies for common diseases.
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#1Nam H. Cho (International Diabetes Federation)H-Index: 56
#2Jonathan E. ShawH-Index: 131
Last. Belma Malanda (International Diabetes Federation)H-Index: 12
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Abstract Introduction Since the year 2000, IDF has been measuring the prevalence of diabetes nationally, regionally and globally. Aim To produce estimates of the global burden of diabetes and its impact for 2017 and projections for 2045. Methods A systematic literature review was conducted to identify published studies on the prevalence of diabetes, impaired glucose tolerance and hyperglycaemia in pregnancy in the period from 1990 to 2016. The highest quality studies on diabetes prevalence were ...
2,384 CitationsSource
#1Jason A. Mendoza (Seattle Children's Research Institute)H-Index: 23
#2Wren Haaland (Seattle Children's Research Institute)H-Index: 13
Last. Angela D. Liese (USC: University of South Carolina)H-Index: 60
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Abstract Aims Household food insecurity (FI), i.e., limited availability of nutritionally adequate foods, is associated with poor glycemic control among adults with type 2 diabetes. We evaluated the association of FI among youth and young adults (YYA) with type 1 diabetes to inform recent clinical recommendations from the American Diabetes Association for providers to screen all patients with diabetes for FI. Methods Using data from the Washington and South Carolina SEARCH for Diabetes in Youth ...
17 CitationsSource
#1Seth A. Berkowitz (Harvard University)H-Index: 28
#2Andrew J. Karter (KP: Kaiser Permanente)H-Index: 84
Last. Deborah J. Wexler (Harvard University)H-Index: 37
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OBJECTIVE Both food insecurity (limited food access owing to cost) and living in areas with low physical access to nutritious foods are public health concerns, but their relative contribution to diabetes management is poorly understood. RESEARCH DESIGN AND METHODS This was a prospective cohort study. A random sample of patients with diabetes in a primary care network completed food insecurity assessment in 2013. Low physical food access at the census tract level was defined as no supermarket wit...
43 CitationsSource
#1Liping Pan (CDC: Centers for Disease Control and Prevention)H-Index: 22
#2Sohyun Park (CDC: Centers for Disease Control and Prevention)H-Index: 31
Last. Heidi M. Blanck (CDC: Centers for Disease Control and Prevention)H-Index: 56
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Importance Severe obesity in childhood is associated with negative health consequences. A previous study examined trends in severe obesity among preschool-aged children in low-income families during 1998 to 2010. No recent trends have been reported. Objective To examine trends in severe obesity by age, sex, and race/ethnicity among enrollees in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) aged 2 to 4 years during 2000 to 2014. Design, Setting, and Participant...
16 CitationsSource
#1Ryan T. Demmer (UMN: University of Minnesota)H-Index: 48
#2Jeremiah A. Barondess (UMN: University of Minnesota)H-Index: 1
The World Health Organization now classifies chronic diseases, including cancer, heart disease, and type 2 diabetes, as noncommunicable. The authors present an alternative way to characterize such ...
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Network biologists, in focusing on interrelational structures emerging from complex interactions among genes, proteins, internal milieu, and external environment, echo the social science view that biomedical reductionism misses crucial aspects of human disease.
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BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in ...
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#1Susanne Röckl (RKI: Robert Koch Institute)H-Index: 1
#2Ralph BrinksH-Index: 19
Last. Christa Scheidt-Nave (RKI: Robert Koch Institute)H-Index: 58
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Objective To estimate age-specific and sex-specific all-cause mortality among adults with and without type 2 diabetes (T2D) in Germany. Research design and methods The German National Health Interview and Examination Survey 1998 (GNHIES98) included a mortality follow-up (median follow-up time 12.0 years) of its nationwide sample representative of the population aged 18–79 years. After exclusion of participants with type 1 diabetes, age- and sex-stratified mortality rates (MR) were calculated for...
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