The 25th Anniversary of the Buchwald–Hartwig Amination: Development, Applications, and Outlook
Volume: 23, Issue: 8, Pages: 1478 - 1483
Published: Jul 2, 2019
Abstract
The palladium-catalyzed cross-coupling of amines and aryl (pseudo)halides, now commonly known as the Buchwald–Hartwig amination, was first reported 25 years ago. Since the simultaneous breakthrough reports of Buchwald and Hartwig in 1995, this reaction has transformed the way synthetic chemists think about synthesizing aromatic amines. In this highlight article, a short showcasing discussion about the genesis of this reaction is provided, along...
Paper Details
Title
The 25th Anniversary of the Buchwald–Hartwig Amination: Development, Applications, and Outlook
Published Date
Jul 2, 2019
Volume
23
Issue
8
Pages
1478 - 1483
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