Evaluation of pre-analytical factors affecting plasma DNA analysis
Abstract
Pre-analytical factors can significantly affect circulating cell-free DNA (cfDNA) analysis. However, there are few robust methods to rapidly assess sample quality and the impact of pre-analytical processing. To address this gap and to evaluate effects of DNA extraction methods and blood collection tubes on cfDNA yield and fragment size, we developed a multiplexed droplet digital PCR (ddPCR) assay with 5 short and 4 long amplicons targeting...
Paper Details
Title
Evaluation of pre-analytical factors affecting plasma DNA analysis
Published Date
May 9, 2018
Journal
Volume
8
Issue
1
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