Pharmacologic targeting of β-catenin improves fracture healing in old mice.

Volume: 9, Issue: 1, Pages: 9005
Published: Jun 21, 2019
Abstract
β-catenin protein needs to be precisely regulated for effective fracture repair. The pace of fracture healing slows with age, associated with a transient increase in β-catenin during the initial phase of the repair process. Here we examined the ability of pharmacologic agents that target β-catenin to improve the quality of fracture repair in old mice. 20 month old mice were treated with Nefopam or the tankyrase inhibitor XAV939 after a tibia...
Paper Details
Title
Pharmacologic targeting of β-catenin improves fracture healing in old mice.
Published Date
Jun 21, 2019
Volume
9
Issue
1
Pages
9005
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