A validation of the diathesis-stress model for depression in Generation Scotland

Volume: 9, Issue: 1
Published: Jan 18, 2019
Abstract
Depression has well-established influences from genetic and environmental risk factors. This has led to the diathesis-stress theory, which assumes a multiplicative gene-by-environment interaction (GxE) effect on risk. Recently, Colodro-Conde et al. empirically tested this theory, using the polygenic risk score for major depressive disorder (PRS, genes) and stressful life events (SLE, environment) effects on depressive symptoms, identifying...
Paper Details
Title
A validation of the diathesis-stress model for depression in Generation Scotland
Published Date
Jan 18, 2019
Volume
9
Issue
1
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