MRI-based measures of intracortical myelin are sensitive to a history of TBI and are associated with functional connectivity
Abstract
Traumatic brain injuries (TBIs) induce persistent behavioral and cognitive deficits via diffuse axonal injury. Axonal injuries are often examined in vivo using diffusion MRI, which identifies damaged and demyelinated regions in deep white matter. However, TBI patients can exhibit impairment in the absence of diffusion-measured abnormalities, suggesting that axonal injury and demyelination may occur outside the deep white matter. Importantly,...
Paper Details
Title
MRI-based measures of intracortical myelin are sensitive to a history of TBI and are associated with functional connectivity
Published Date
Oct 1, 2019
Journal
Volume
200
Pages
199 - 209
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Notes
History