Reversible ADP-ribosylation of RNA
Abstract
ADP-ribosylation is a reversible chemical modification catalysed by ADP-ribosyltransferases such as PARPs that utilize nicotinamide adenine dinucleotide (NAD+) as a cofactor to transfer monomer or polymers of ADP-ribose nucleotide onto macromolecular targets such as proteins and DNA. ADP-ribosylation plays an important role in several biological processes such as DNA repair, transcription, chromatin remodelling, host-virus interactions, cellular...
Paper Details
Title
Reversible ADP-ribosylation of RNA
Published Date
Apr 26, 2019
Journal
Volume
47
Issue
11
Pages
5658 - 5669
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Notes
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