A pan-cancer analysis of synonymous mutations.
Abstract
Synonymous mutations have been viewed as silent mutations, since they only affect the DNA and mRNA, but not the amino acid sequence of the resulting protein. Nonetheless, recent studies suggest their significant impact on splicing, RNA stability, RNA folding, translation or co-translational protein folding. Hence, we compile 659194 synonymous mutations found in human cancer and characterize their properties. We provide the user-friendly,...
Paper Details
Title
A pan-cancer analysis of synonymous mutations.
Published Date
Jun 12, 2019
Journal
Volume
10
Issue
1
Pages
2569 - 2569
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