Pseudomonas aeruginosa

Bacteria

Biology

Surgery

Fibrosis

Immunity

Immune Dysfunction

Dysfunctional family

Immunology

Airway

Cystic fibrosis

Genetics

Immune system

Pathophysiology

Microbiology

Internal medicine

Medicine

Clinical psychology

Pathology

Clinical Microbiology Reviews

In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with chronic pulmonary infections wreak havoc upon the airway, leading to a disease course of substantial morbidity and shortened life span.

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface