MicroRNA-9 enhanced radiosensitivity and its mechanism of DNA methylation in non-small cell lung cancer
Abstract
In order to improve the therapeutic effect of non-small cell lung cancer (NSCLC), it is critical to combine radiation and gene therapy. Our study found that the activation of microRNA-9 (miR-9) conferred ionizing radiation (IR) sensitivity in cancer cells. Furthermore, increased microRNA-9 promoter methylation level was observed after IR. Our study combined the IR and microRNA-9 overexpression treatment which leads to a significant enhancement...
Paper Details
Title
MicroRNA-9 enhanced radiosensitivity and its mechanism of DNA methylation in non-small cell lung cancer
Published Date
Aug 1, 2019
Journal
Volume
710
Pages
178 - 185
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