miR-301a promotes lung tumorigenesis by suppressing Runx3

Volume: 18, Issue: 1
Published: May 23, 2019
Abstract
Our previous report demonstrated that genetic ablation of miR-301a reduces Kras-driven lung tumorigenesis in mice. However, the impact of miR-301a on host anti-tumor immunity remains unexplored. Here we assessed the underlying molecular mechanisms of miR-301a in the tumor microenvironment. The differentially expressed genes were identified by using deep sequencing. The immune cell counts, and cytokines expression were analyzed by realtime PCR,...
Paper Details
Title
miR-301a promotes lung tumorigenesis by suppressing Runx3
Published Date
May 23, 2019
Volume
18
Issue
1
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