Neuroscience

Elevated plus maze

Social defeat

Physiology

Endocrinology

Psychiatry

Developmental psychology

Psychology

Hypothalamus

Amygdala

Aggression

Corticosterone

Anxiety

Adult male

Hormone

Medicine

Biological Psychiatry

Despite the twofold higher prevalence of major depressive and posttraumatic stress disorders in women compared with men, most clinical and preclinical studies have focused on male subjects. We used an ethological murine model to study several cardinal symptoms of affective disorders in the female targets of female aggression.

Fighting Females: Neural and Behavioral Consequences of Social Defeat Stress in Female Mice