Osteogenic potential of zingerone, a phenolic compound in mouse mesenchymal stem cells

Zingerone, 4‐(4‐hydroxy‐3‐methoxyphenyl)‐2‐butanone (Zg), a phenolic compound isolated from ginger is reported to have anti‐inflammatory and antidiabetic properties. However, its role in the promotion of osteogenesis is not known. In this study, we investigated the therapeutic effect of Zg on osteogenesis at the cellular and molecular levels. Zg treatment was nontoxic to mouse mesenchymal stem cells (mMSCs). At the cellular level, it enhanced...