Metabolomic profiling for identification of potential biomarkers in patients with dermatomyositis

Dermatomyositis (DM) is a rare autoimmune myopathy characterized by skin lesions, proximal muscle weakness and muscle inflammation. The pathogenesis of DM is unclear, and identification of reliable biomarkers for early diagnosis of DM is critical for design of a specific therapy for this disease. To find and identify potential serum biomarkers in DM patients. We performed an untargeted metabolomic approach using UHPLC-MS/MS. The blood serum...