Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction coupled with column chromatography

Volume: 224, Pages: 397 - 404
Published: Oct 1, 2019
Abstract
Separation and purification of secondary metabolites from wild microorganisms remains a challenge due to the analogues existing in the fermentation broth. In this study, a three-liquid-phase salting-out extraction system (TLP-SOES) coupled with column chromatography was developed to purify wortmannilactone F and its dehydrated derivative wortmannilactone L. The TLP-SOES composed of 25.5% petroleum ether/20.0% ethanol/12.9% ammonium sulfate (w/w)...
Paper Details
Title
Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction coupled with column chromatography
Published Date
Oct 1, 2019
Volume
224
Pages
397 - 404
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.