Porous microspheres based on hydroxyapatite-graft-poly (γ-benzyl-l-glutamate) with improving homogeneity of hydroxyapatite and osteogenesis

Porous microspheres, which can provide sufficient internal space for cell in-growth and protect cells during injection have attracted widespread attention in bone tissue engineering. Hydroxyapatite (HA)/polymer composite scaffolds have been fabricated for bone tissue engineering. The combination between HA and polymer matrix generally includes two modes, physical mixing and chemical grafting. Deciding which combination mode have better effect on...