SUN-193 Effects of Aldosterone on Ovarian Steroidogenesis and Involvement of BMP Action in Rat Granulosa Cells

Many local factors expressed in the ovary are involved in folliculogenesis. Among these, the ovarian renin-angiotensin system is critical for normal processes of follicle development, steroidogenesis and ovulation. In various clinical conditions such as secondary hypertension, heart failure, and liver and/or renal damages, hyperaldosteronism can be detected. In addition, Aldo levels are known to be high in patients with PCOS and/or OHSS....