A prospective evaluation of liquid biopsy for detecting MYCN amplification in neuroblastoma patients

Volume: 49, Issue: 8, Pages: 743 - 748
Published: May 4, 2019
Abstract
Background Our previous study reported a method for determining MYCN gene amplification (MNA) status using cell-free DNA in serum. We prospectively analyzed the serum MNA status using sera obtained before the initial diagnosis from patients with neuroblastoma and evaluated the utility of this method. Methods Eighty patients were enrolled in the study. The serum MYCN/NAGK ratio was assessed for all cases. Results Fifteen cases showed serum MNA,...
Paper Details
Title
A prospective evaluation of liquid biopsy for detecting MYCN amplification in neuroblastoma patients
Published Date
May 4, 2019
Volume
49
Issue
8
Pages
743 - 748
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