What has single-cell RNA-seq taught us about mammalian spermatogenesis?
Abstract
Mammalian spermatogenesis is a complex developmental program that transforms mitotic testicular germ cells (spermatogonia) into mature male gametes (sperm) for production of offspring. For decades, it has been known that this several-weeks-long process involves a series of highly ordered and morphologically recognizable cellular changes as spermatogonia proliferate, spermatocytes undertake meiosis, and spermatids develop condensed nuclei,...
Paper Details
Title
What has single-cell RNA-seq taught us about mammalian spermatogenesis?
Published Date
May 11, 2019
Journal
Volume
101
Issue
3
Pages
617 - 634
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History