Human Gut-Associated Natural Killer Cells in Health and Disease

It is well established that natural killer (NK) cells are involved in both innate and adaptive immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals and virus infections. In the gut, their function is much more complex: indeed, they are not precisely organized in lymphoid aggregates, but rather scattered in the epithelium or in the stroma, where they come in contact with a multitude of antigens derived from...