Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells
Abstract
Dental follicle cells (DFCs) are dental stem cells and interesting options for regenerative therapies in dentistry. However, DFCs acquire replicative senescence in long-term cultures, but little is known about molecular processes. In previous studies, we observed that DFC cell lines become senescent at different rates. We hypothesized that short telomere length and increased DNA damage with genomic instability correlate with the accelerated...
Paper Details
Title
Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells
Published Date
Apr 3, 2019
Volume
20
Issue
1
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