microRNA‐23a contributes to asthma by targeting BCL2 in airway epithelial cells and CXCL12 in fibroblasts

The deregulated cross‐talk between airway epithelial cells with subepithelial fibroblasts during inflammation drives the pathogenesis of asthma. Bioinformatics analysis and luciferase activity assay suggested that B cell lymphoma‐2 (BCL2) and CXC ligand 12 (CXCL12) are potential targets of miR‐23a. The aim of this study was to elucidate the effect of microRNA‐23a (miR‐23a) on BCL2, and CXCL12 in asthma. In E3 rats, miR‐23a was upregulated in...