0903 Links between Objective Sleep Measures and Inflammation in Adults with Bipolar Disorder: Examination of Variability Assessments

Sleep disturbances are central to bipolar disorder (BD), with clear implications for psychopathology. In the general population, actigraphy-assessed sleep disturbances have been linked with heightened inflammation. However, in BD, relationships of the degree of sleep disturbance and variability to inflammatory biomarker levels has not been shown. The cross-sectional study includes 35 euthymic subjects with BD (DSM-IV-TR criteria), and 57...