Intratumoral Heterogeneity: More Than Just Mutations
Abstract
Most human tumors are composed of genetically and phenotypically heterogeneous cancer cell populations, which poses a major challenge for the clinical management of cancer patients. Advances of single-cell technologies have allowed the profiling of tumors at unprecedented depth, which, in combination with newly developed computational tools, enable the dissection of tumor evolution with increasing precision. However, our understanding of...
Paper Details
Title
Intratumoral Heterogeneity: More Than Just Mutations
Published Date
Jul 1, 2019
Journal
Volume
29
Issue
7
Pages
569 - 579
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Notes
History