Efficient induction of heritable inversions in plant genomes using theCRISPR/Cas system

Volume: 98, Issue: 4, Pages: 577 - 589
Published: Mar 22, 2019
Abstract
Summary During the evolution of plant genomes, sequence inversions occurred repeatedly making the respective regions inaccessible for meiotic recombination and thus for breeding. Therefore, it is important to develop technologies that allow the induction of inversions within chromosomes in a directed and efficient manner. Using the Cas9 nuclease from Staphylococcus aureus ( Sa Cas9), we were able to obtain scarless heritable inversions with high...
Paper Details
Title
Efficient induction of heritable inversions in plant genomes using theCRISPR/Cas system
Published Date
Mar 22, 2019
Volume
98
Issue
4
Pages
577 - 589
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