Improving cellular uptake of therapeutic entities through interaction with components of cell membrane
Abstract
Efficient cellular delivery of biologically active molecules is one of the key factors that affect the discovery and development of novel drugs. The plasma membrane is the first barrier that prevents direct translocation of chemic entities, and thus obstructs their efficient intracellular delivery. Generally, hydrophilic small molecule drugs are poor permeability that reduce bioavailability and thus limit the clinic application. The cellular...
Paper Details
Title
Improving cellular uptake of therapeutic entities through interaction with components of cell membrane
Published Date
Jan 1, 2019
Journal
Volume
26
Issue
1
Pages
328 - 342
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Notes
History