CD28null CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection

Volume: 8, Pages: 327 - 327
Published: Mar 25, 2019
Abstract
Immunosenescence is thought to contribute to the increase of autoimmune diseases in older people. Immunosenescence is often associated with the presence of an expanded population of CD4 T cells lacking expression of CD28 (CD28null). These highly cytotoxic CD4 T cells were isolated from disease-affected tissues in patients with rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, or other chronic...
Paper Details
Title
CD28null CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection
Published Date
Mar 25, 2019
Volume
8
Pages
327 - 327
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